Could you help me with genetics?

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Could you help me with genetics?

Post by peached on Tue Sep 10, 2013 2:58 pm

I'm wondering the possible outcomes of two mice. I'd want to know probability of coat type, eye color, coat color.

The doe is a RY piebald, standard coat with pink eyes. The buck is dove self, long hair with pink eyes.

I do not know the parents but I know the siblings. The doe had 3 sisters who were standard coat, black eyed, black piebald and a sister who was long hair, RY piebald with black eyes.
I only know the buck had a brother who was dove piebald who was also long hair.

Does it make any difference if I know the siblings in predicting litters if I do not know what the parents were?

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Re: Could you help me with genetics?

Post by Trixie's Mice on Wed Sep 11, 2013 7:03 pm

Hello there, yes it does help if you know the siblings. Happy

Your female is: a/a e/e p/p Lgh/* since he sis was long haired, she has a good chance of carrying it (50% chance or 100%).
a/a is black
e/e is the RY changing the black to yellow
p/p is pink eyes
Lgh/* is non long hair
lgh/lgh is long hair

Your male is: a/a E/* p/p lgh/lgh (he is most likely E/E there is a small chance of him carrying RY Wink)

So the out come would be (assuming that the male doesn't carry RY): All "Dove" and 50% standard coats and if the female dos carry long hair then 50% long hair. If she doesn't it would be 100% standard.

Assuming that the mom is a/a e/e p/p Lgh/lgh and dad is a/a E/E p/p lgh/lgh the babies genotype would be 50% a/a E/e p/p Lgh/lgh and 50% a/a E/e p/p lgh/lgh.

If this is confusing let me know. Happy Good luck! And I hope she does carry long hair.
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Re: Could you help me with genetics?

Post by peached on Wed Sep 11, 2013 10:19 pm

Wow thanks! That all makes sense. You explained it well.

One more question, could the buck carry the piebald gene if his dove brother was piebald?

I hope she carries long hair too!

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Re: Could you help me with genetics?

Post by Trixie's Mice on Thu Sep 12, 2013 1:45 pm

Oh I'm sorry... for some reason I apparently have something against pied hahha.

Yes, add the s/s to her genotype. The male has a 50% or 100% chance of carrying pied (s/s) for now he is S/*. I hope he carries it (S/s).
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Re: Could you help me with genetics?

Post by peached on Thu Sep 12, 2013 7:01 pm

Thank you! Not only did you answer my questions but I have a better understanding of mouse genetics now

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Re: Could you help me with genetics?

Post by Trixie's Mice on Thu Sep 12, 2013 7:06 pm

I'm happy to help. I love talking about genetics and mice. Let me know if you have any other questions. Happy
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